Siranjeevi Gurumani

Skills

Experiences

1. 

   MetFlux Research

   May 2022 - Feb 2024

   Decision Scientist

   1) Handling Systems Biology Modelling: - Developed and managed a comprehensive whole-body energy balance model, integrating various metabolic pathways and regulatory mechanisms. - Worked with liver metabolism model 2) Product Intervention Evaluation: - Conducted product intervention evaluations, particularly in the realm of health and nutrition drinks, and assessed the prebiotic and probiotic effects. - Applied sensitivity analysis techniques to evaluate the robustness of models and identify key parameters influencing outcomes. - Investigated the impact of macronutrients and micronutrients on model behavior. - Optimized model parameters to accurately replicate experimental data, ensuring model validity and reliability. - Utilized population generation and analysis methods to account for inter-individual variability and assess population-level responses. 3) Conversion of Glucose-Insulin Simbiology Model: - Successfully converted a Glucose-Insulin Simbiology model into script functions, enhancing efficiency and flexibility in model implementation and analysis. 4) Pharmacokinetics Compartmental Modelling: - Developed and generalized an automated framework for building n-compartment pharmacokinetic models, streamlining the model development process. - Implemented a user-friendly interface allowing input of data as an array, facilitating model construction, data fitting, prediction and analysis. 5) Report Generator and Model Simulation: - Designed and implemented a report generator coupled with model simulation capabilities, enabling seamless integration of model outputs into comprehensive reports. - Automated result pasting functionality, enhancing efficiency and accuracy in report generation and data presentation.

Education

1. 

   IIT Delhi

   Jul 2018 - May 2022

   M.S(research)

   Biological science
2. 

   NIT Warangal

   Aug 2014 - May 2018

   B.Tech

   Biotechnology